Therapeutic Drug Monitoring (TDM)

Healthcare Intervention Management in the 21st century

Drug and medication management and monitoring play a huge and central role in medicine in the 21st century. It has always been crucial to get the drug right both in content and in quantity (dosage), but it has (and in many cases still is) been done by a manual operation.

In other words, giving the patient the correct drug in the correct dose and at the correct timing may make the different between life and death, but it is left to the physicians and nurses to utilize their knowledge of the drug, the ailment and the patient.

Therapeutic Drug Monitoring

Therapeutic Drug Monitoring, or TDM as it is also known, is a field in pharmacology, which deals with the measurement and monitoring of drug concentration in the blood stream. However, TDM isn’t only applied after the patient is given a drug, but also before.

This is called a priori Therapeutic Drug Monitoring and it is the field of “determining the initial dose regimen to be given to a patient, based on clinical endpoint and on established population pharmacokinetic-pharmacodynamic (PK/PD) relationships. These relationships help to identify sub-populations of patients with different dosage requirements, by utilizing demographic data, clinical findings, clinical chemistry results, and/or, when appropriate, pharmacogenetic characteristics”. (source: Wikipedia)


Automated Medication Management as a tool for personalized medicine

RescueDose’s technology is positioned to lead the niche of personalized pahramacology and personalized medicine. In order to deliver and ensure high quality a priori TDM the human aspect in the process has to be minimized. Medical staff are human beings and they are affected by many things, as we all are. Even with all the knowledge they possess, medication errors and other treatment related risks sill occur. This is why an automated process and system which utilizes a database of knowledge and personal information about the patient to calculate the accurate dosage and timing and dispense the medication in a “ready to use” form, is crucial.